Dr. Tom Biernacki, DPM, FACFAS 
Sperm DNA fragmentation above 25% dramatically reduces IVF success rates. Dr. Tom’s preconception protocol targets CoQ10 for oocyte mitochondrial function, folate forms, and the 90-day sperm repair window.
Low-dose naltrexone reduces microglial activation and TLR4 signaling in rheumatoid arthritis — with a safety profile that DMARDs can’t match. Dr. Tom reviews the LDN evidence and omega-3 EPA dosing for joint inflammation.
Astaxanthin is 6,000x more potent than vitamin C as an antioxidant and crosses the blood-brain barrier. Dr. Tom reviews its mitochondrial protective effects in diabetic peripheral nerve damage.
The HPA axis doesn’t ‘burn out’ — it dysregulates. Dr. Tom uses the DUTCH Complete test to map cortisol curves, DHEA-S trends, and the 4-phase cortisol pattern that reveals whether adaptogens are actually indicated.
[medical-review-box] Medically Reviewed by Dr. Nnamdi Gwacham, DPM | Board-Certified Podiatrist, Balance Foot & Ankle | Howell, MI & Bloomfield Hills, MI [/medical-review-box] [quick-answer-box] Quick Answer: Melatonin reduces diabetic neuropathy through three distinct mechanisms: (1) MT2 receptor/Gαi signaling reduces cAMP/PKA activity in DRG nociceptors, suppressing HCN1 hyperpolarization-activated current (Ih) and lowering the pacemaker depolarization that … Read more
Quick answer: Human lifespan is not fixed — it is the product of nine measurable, modifiable “hallmarks of aging” that can be targeted with precision interventions. Senolytics clear the inflammatory zombie cells that accelerate aging; NAD+ precursors restore mitochondrial efficiency; mTOR inhibition via fasting and rapamycin mimics the gene expression of caloric restriction; and VO2max … Read more
[medical-review-box] Medically Reviewed by Dr. Nnamdi Gwacham, DPM | Board-Certified Podiatrist, Balance Foot & Ankle | Howell, MI & Bloomfield Hills, MI [/medical-review-box] [quick-answer-box] Quick Answer: Nicotinamide riboside (NR) repairs diabetic neuropathy through three mechanisms: (1) NR → NAD⁺ → SIRT1 deacetylates PGC-1α Lys183 to activate the PGC-1α/NRF1/Tfam mitochondrial biogenesis axis in Schwann cells, restoring … Read more
The SMILES trial showed a Mediterranean diet reduced depression scores 3x better than social support. Dr. Tom combines SMILES findings with omega-3 EPA dosing and MTHFR-specific methylfolate protocols for treatment-resistant depression.
Sulforaphane is the most potent natural Nrf2 activator — upregulating over 200 cytoprotective genes in peripheral nerve tissue. Dr. Tom reviews the broccoli sprout protocol and sulforaphane’s neuroprotective evidence base.
Acne, psoriasis, and hair loss share a common thread: systemic inflammation driven by gut dysbiosis and elevated androgens. Dr. Tom’s functional dermatology protocol targets root causes instead of topical suppression.