Evidence-based health, wellness, and longevity content from Dr. Tom Biernacki.
Cancer thrives on glucose via the Warburg effect. Dr. Tom reviews the metabolic theory of cancer, insulin signaling, and integrative protocols used alongside standard treatment.
Fisetin clears senescent cells, reduces advanced glycation end-products, and protects axons in diabetic neuropathy models. Dr. Tom reviews dosing, bioavailability, and clinical relevance.
Free testosterone, SHBG, LH, FSH — Dr. Tom’s functional medicine approach to men’s hormonal health, lifestyle optimization, and when TRT is actually the right call.
Luteolin blocks NF-κB and NLRP3 inflammasome activation in peripheral nerves, reducing pain signaling in diabetic neuropathy models. Dr. Tom reviews the evidence and protocol dosing.
VO2 max is the single strongest predictor of all-cause mortality. Dr. Tom covers Zone 2 heart rate targets, creatine loading for athletes, and how the gut microbiome controls endurance adaptation.
PFAS, mercury, arsenic, and mycotoxins are stored in fat and disrupt hormones, mitochondria, and the immune system. Dr. Tom’s environmental medicine detox protocol — with labs and timeline.
Apigenin inhibits CD38, the enzyme that depletes NAD+, restoring mitochondrial function in diabetic nerves. Dr. Tom reviews its evidence base and how it stacks with NMN or NR.
Perimenopause begins 8–10 years before the final period. Dr. Tom explains DUTCH hormone testing, estradiol-to-progesterone ratios, bioidentical HRT timing, and symptom-driven protocol design.
Hesperidin from citrus peel reduces sorbitol accumulation and PKC activation in diabetic peripheral nerves. Dr. Tom reviews its evidence base and how it complements other flavonoid interventions.
Up to 33% of depressed patients have elevated inflammatory markers. Dr. Tom’s functional psychiatry approach covers omega-3 EPA dosing, kynurenine pathway, gut dysbiosis, and lithium orotate.