Health & Wellness

Diosmin reduces vascular permeability and nerve edema in diabetic neuropathy. Dr. Tom reviews its microvascular mechanisms, comparison to hesperidin, and its role in a neuropathy protocol.

The estrobolome — estrogen-metabolizing gut bacteria — drives endometriosis progression. Dr. Tom explains the estrogen-gut-immune axis and the functional medicine protocols that reduce disease burden.

PCOS affects 10% of women of reproductive age — most have insulin resistance as the root driver. Dr. Tom covers myo-inositol, berberine, metformin alternatives, and the labs that guide treatment.

Bone loss accelerates after 35 — but DEXA scans miss early decline. Dr. Tom covers optimal vitamin D3/K2 dosing, the role of magnesium and boron, and resistance training for bone density.

Silybin, the active flavonolignan in milk thistle, activates Nrf2, reduces hepatic AGE production, and protects Schwann cells in diabetic neuropathy models. Dr. Tom reviews its evidence.

Rheumatoid arthritis begins in the gut — specific microbiome signatures predict RA years before joint symptoms. Dr. Tom explains leaky gut, molecular mimicry, and the functional rheumatology protocol.

Baicalein, the primary active flavone in Scutellaria baicalensis, inhibits 12-LOX and reduces arachidonic acid-driven inflammation in peripheral nerves. Dr. Tom’s evidence review and dosing protocol.

Icariin from Epimedium inhibits PDE5, increases cGMP, and promotes nerve growth factor expression in diabetic neuropathy models. Dr. Tom reviews its evidence and protocol relevance.

Fibromyalgia is central sensitization — the nervous system amplifying pain signals. Dr. Tom covers the neuroinflammation model, low-dose naltrexone, sleep restoration, and the labs that guide treatment.

Burnout isn’t just stress — it’s measurable cortisol dysregulation. Dr. Tom uses the DUTCH test to assess HPA axis patterns and guides evidence-based adaptogen protocols.