Luteolin for Diabetic Neuropathy
Luteolin directly suppresses microglial TLR4 signaling — the key driver of neuroinflammatory pain in diabetic neuropathy. Dr. Tom reviews its dual peripheral and central mechanisms and clinical dosing.
Evidence-based health, wellness, and longevity content from Dr. Tom Biernacki.
Luteolin directly suppresses microglial TLR4 signaling — the key driver of neuroinflammatory pain in diabetic neuropathy. Dr. Tom reviews its dual peripheral and central mechanisms and clinical dosing.
NAFLD affects 1 in 3 Americans and often has no symptoms. Dr. Tom covers the metabolic drivers of fatty liver, berberine vs. GLP-1, choline deficiency, and the labs that track liver fat regression.
Carnosine directly quenches advanced glycation end-products before they damage peripheral nerves. Dr. Tom reviews carnosine’s anti-glycation mechanisms, the evidence in diabetic neuropathy, and optimal dosing.
The glymphatic system clears Alzheimer’s-related proteins during deep sleep — you can’t detox your brain if you’re not sleeping. Dr. Tom covers circadian biology, OSA, and the functional sleep protocol.
Cancer cells ferment glucose 200x faster than normal cells — the Warburg effect. Dr. Tom explains insulin’s role in tumor growth, the metabolic prevention strategies, and integrative oncology’s evidence base.
Diabetics have dramatically reduced taurine in peripheral nerve tissue — depleted by the polyol pathway. Dr. Tom reviews taurine’s role in osmotic balance, calcium buffering, and nerve conduction restoration.
Acid-blocking drugs treat GERD symptoms but worsen SIBO and H. pylori — they lower acid that kills bacteria. Dr. Tom explains low stomach acid as the root cause and the testing + repair sequence that works.
Mitochondrial dysfunction in peripheral nerves drives the burning and tingling of diabetic neuropathy. Dr. Tom reviews CoQ10’s electron transport chain support, ubiquinol vs. ubiquinone dosing, and clinical evidence.
Dr. Dale Bredesen’s ReCODE protocol has reversed cognitive decline in published case series. Dr. Tom walks through the 36 metabolic drivers, the required labs, and the step-by-step implementation framework.
Quercetin is both a senolytic and AMPK activator — clearing senescent cells and improving mitochondrial function in diabetic peripheral nerves. Dr. Tom reviews dosing, bioavailability, and stacking with fisetin.